Boston University

Optical Characterization and Nanophotonics Laboratory








[Journal Articles]

Colin Worth

Graduate Research Assistant
Doctor of Philosophy
Boston University
66 Grove Hill Ave.
Newton, MA 02160


Evanescent Waveguide Biosensors


Colin Worth received his B.S. in Physics from Haverford College in Pennsylvania, where he worked on the control system for a Scanning Tunneling Microscope with Walter Smith, and his M.S. and Ph.D. degrees in Physics from Boston University, where he worked with Bennett Goldberg and Selim Unlu (both joint professors of Physics and Electrical Engineering) in collaboration with an industrial partner to develop a novel optical waveguide biosensor for surface sensing applications. Goldberg, Unlu, and Worth filed and received a patent for their original method of reducing the noise associated with non-specific binding of nanometer sized particles to the waveguide surface by tuning the optical properties of the waveguide.

After receiving his Ph.D. in May 2005, Worth joined Photodetection Systems, an angel funded small business founded by William Worstell of Boston University and the BU Photonics Center to develop low-dose, high sensitivity Positron Emission Tomography (PET) scanners for clinical and research applications. At Photodetection Systems, Worth worked on a project to produce a portable standalone scanner for neurological research and drug development and participated in a collaboration with an established CT manufacturer to design and produce a novel full body large-bore PET/CT scanner. Worth worked on the improvement of PET reconstruction and data correction algorithms, and was instrumental in replacing the prototype processing and control software with robust, high-speed C++ code running in real time on a twelve node parallel computing cluster. Both scanners achieved professional, market-ready levels of performance and reliability and were granted 510k certification by the FDA.

Journal Articles

1.) C. Worth, B. B. Goldberg, M. F. Ruane, and M. S. Ünlü, "Surface Desensitization of Polarimetric Waveguide Interferometers," IEEE Journal of Selected Topics in Quantum Electronics, Vol. 7, No. 6, November/December 2001, pp. 874-877

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