Boston University

Optical Characterization and Nanophotonics Laboratory

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[Patents][Books & Chapters][Journal Articles][Conference Papers]

David S. Freedman

Research Associate
Doctor of Philosophy
8 St. Mary's Street
Boston, MA 02215
Office: (617) 358-4131
Lab: (617) 353-5887

Projects

Interferometric Reflectance Imaging Sensor

Opto-Electrical Wireless Neural Stimulators

Patents

1.) M. Sahin, M. S. Ünlü, D. S. Freedman, and A. Abdo, "SYSTEM AND METHOD FOR NEURAL STIMULATION VIA OPTICALLY ACTIVATED FLOATING MICRODEVICES," United States Patent Issued, No. US 9,526,904 B2, 27 December 2016

Books & Chapters

3.) D. S. Freedman, M. Sahin, and B. C. Towe, "Wireless Microstimulators," Encyclopedia of Computational Neuroscience, November 2013

2.) X. Zhang, P. S. Spuhler, D. S. Freedman, and M. S. Ünlü, "Spectral Self-Interference Fluorescence Microscopy to Study Conformation of Biomolecules with Nanometer Accuracy," Nanoscale Spectroscopy with Applications, November 2013

1.) S. Ahn, D. S. Freedman, X. Zhang, and M. S. Ünlü, "High-throughput label-free detection of DNA hybridization and mismatch discrimination using interferometric reflectance imaging sensor," Nucleic Acid Detection: Methods in Molecular Biology, Vol. 1039, September 2013

Journal Articles

9.) G. G. Daaboul, P. Gagni, L. Benussi, P. Bettotti, M. Ciani, M. Cretich, D. S. Freedman, R. Ghidoni, A. Yalcin, C. Piotto, D. Prosperi, B. Santini, M. S. Ünlü, and M. Chiari, "Digital Detection of Exosomes by Interferometric Imaging ," Nature Scientific Reports, Vol. 6, 37246; DOI:, No. 10.1038/srep37246, 17 November 2016

8.) L. Wang, D. S. Freedman, M. Sahin, M. S. Ünlü, and R. W. Knepper, "Active C4 Electrodes for Local Field Potential Recording Applications," Sensors, Vol. 16, No. 2, 4 February 2016, pp. 198

7.) A. Ersen, S. Elkabes, D. S. Freedman, and M. Sahin, "Chronic tissue response to untethered microelectrode implants in the rat brain and spinal cord," Journal of Neural Engineering, Vol. 12, No. 1, 21 January 2015, pp. 016019

6.) X. Zhang, G. G. Daaboul, P. S. Spuhler, D. S. Freedman, A. Yurt, S. Ahn, O. Avci, and M. S. Ünlü, "Nanoscale Characterization of DNA Conformation Using Dual-color Fluorescence Axial Localization and Label-free Biosensing," Analyst, 13 October 2014

5.) C. Yu, C. A. Lopez, H. Hu, Y. Xia, D. S. Freedman, A. Reddington, G. G. Daaboul, M. S. Ünlü, and C. A. Genco, "A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein Fur.," PLoS ONE, Vol. 9, No. 5, May 2014

4.) E. Cevik, D. S. Freedman, M. Gökkavas, E. Özbay, M. Sahin, and M. S. Ünlü, "Improved selectivity from a wavelength addressable device for wireless stimulation of neural tissue," Frontiers in Neuroengineering, Vol. 7, No. 00005, 18 February 2014, pp. 1-12

3.) A. Reddington, J. T. Trueb, D. S. Freedman, A. Tuysuzoglu, G. G. Daaboul, C. A. Lopez, W. C. Karl, J. H. Connor, H. E. Fawcett, and M. S. Ünlü, "An Interferometric Reflectance Imaging Sensor for Point of Care Viral Diagnostics," IEEE Transactions on Biomedical Engineering, Vol. 60, No. 12, December 2013, pp. 3276-3283

2.) S. Ahn, D. S. Freedman, P. Massari, M. Cabodi, and M. S. Ünlü, "A Mass-Tagging Approach for Enhanced Sensitivity of Dynamic Cytokine Detection Using a Label-Free Biosensor," Langmuir, Vol. 29, No. 17, April 2013, pp. 5369-5376

1.) A. Abdo, M. Sahin, D. S. Freedman, E. Cevik, P. S. Spuhler, and M. S. Ünlü, "Floating light-activated microelectrical stimulators tested in the rat spinal cord," Journal of Neural Engineering, Vol. 8, No. 5, October 2011

Conference Papers

4.) X. Zhang, G. G. Daaboul, P. S. Spuhler, D. S. Freedman, A. Yurt, S. Ahn, and M. S. Ünlü, "Quantification of DNA hybridization by nanoscale axial localization and label-free biosensing," BMES 2013 Annual Meeting , 22-25 October 2013

3.) L. Wang, D. S. Freedman, R. W. Knepper, M. S. Ünlü, and M. Sahin, "A 16 × 16 Multi-electrode Array with Integrated CMOS Amplifiers for Neural Signal Recording," Biomedical Circuits and Systems Conference, 2011, November 2011

2.) A. Abdo, M. Sahin, D. S. Freedman, E. Cevik, P. S. Spuhler, and M. S. Ünlü, "Intraspinal Stimulation with Light Activated Micro-Stimulators," 5th International IEEE EMBS Conference on Neural Engineering, 29 April 2011

1.) D. S. Freedman, P. S. Spuhler, E. Cevik, M. S. Ünlü, and M. Sahin, "Addressable Floating Light Activated Micro-Electrical Stimulators for Wireless Neurostimulation," 5th International IEEE EMBS Conference on Neural Engineering, 29 April 2011

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