Boston University

Optical Characterization and Nanophotonics Laboratory

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[Journal Articles][Conference Papers]

George Gaby Daaboul

Collaborator
Doctor of Philosophy
Boston University
Boston, MA

Projects

Interferometric Reflectance Imaging Sensor

Biological Sensors

Platform for Quantified High-throughput Measurement of Protein Induced Conformation Changes in DNA

Journal Articles

19.) G. G. Daaboul, P. Gagni, L. Benussi, P. Bettotti, M. Ciani, M. Cretich, D. S. Freedman, R. Ghidoni, A. Yalcin, C. Piotto, D. Prosperi, B. Santini, M. S. Ünlü, and M. Chiari, "Digital Detection of Exosomes by Interferometric Imaging ," Nature Scientific Reports, Vol. 6, 37246; DOI:, No. 10.1038/srep37246, 17 November 2016

18.) S. M. Scherr, G. G. Daaboul, J. T. Trueb, D. D. Sevenler, H. E. Fawcett, B. B. Goldberg, J. H. Connor, and M. S. Ünlü, "Real-Time Capture and Visualization of Individual Viruses in Complex Media," Acs Nano, No. DOI: 10.1021/acsnano, January 2016

17.) X. Zhang, G. G. Daaboul, P. S. Spuhler, P. Dröge, and M. S. Ünlü, "Quantitative characterization of conformational-specific protein–DNA binding using a dual-spectral interferometric imaging biosensor," Nanoscale, No. DOI: 10.1039/C5NR067, 2016

16.) E. Cevik, G. G. Daaboul, X. Zhang, S. M. Scherr, N. Lortlar Ünlü, J. H. Connor, and M. S. Ünlü, "DNA-Directed Antibody Immobilization for Enhanced Detection of Single Viral Pathogens," Analytical Chemistry, Vol. 87, No. 20, October 2015, pp. 10505-10512, DOI:10.1021/acs.analchem.5b02702

15.) M. Cretich, G. G. Daaboul, L. Sola, M. S. Ünlü, and M. Chiari, "Digital detection of biomarkers assisted by nanoparticles: application to diagnostics," Trends in Biotechnology, 2015

14.) X. Zhang, G. G. Daaboul, P. S. Spuhler, D. S. Freedman, A. Yurt, S. Ahn, O. Avci, and M. S. Ünlü, "Nanoscale Characterization of DNA Conformation Using Dual-color Fluorescence Axial Localization and Label-free Biosensing," Analyst, 13 October 2014

13.) G. G. Daaboul, C. A. Lopez, J. Chinnala, B. B. Goldberg, J. H. Connor, and M. S. Ünlü, "Digital Sensing and Sizing of Vesicular Stomatitis Virus Pseudotypes in Complex Media: A Model for Ebola and Marburg Detection," Acs Nano, Vol. 8, No. 6, 19 May 2014, pp. 6047–6055

12.) C. Yu, C. A. Lopez, H. Hu, Y. Xia, D. S. Freedman, A. Reddington, G. G. Daaboul, M. S. Ünlü, and C. A. Genco, "A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein Fur.," PLoS ONE, Vol. 9, No. 5, May 2014

11.) X. X. Cheng, G. G. Daaboul, M. S. Ünlü, and K. Kerman, "LED-based interferometric reflectance imaging sensor for the detection of amyloid-b aggregation," Analyst, Vol. 139, No. DOI: 10.1039/c3an013, January 2014, pp. 59-65

10.) A. Reddington, J. T. Trueb, D. S. Freedman, A. Tuysuzoglu, G. G. Daaboul, C. A. Lopez, W. C. Karl, J. H. Connor, H. E. Fawcett, and M. S. Ünlü, "An Interferometric Reflectance Imaging Sensor for Point of Care Viral Diagnostics," IEEE Transactions on Biomedical Engineering, Vol. 60, No. 12, December 2013, pp. 3276-3283

9.) M. R. Monroe, G. G. Daaboul, A. Tuysuzoglu, C. A. Lopez, F. F. Little, and M. S. Ünlü, "Single Nanoparticle Detection for Multiplexed Protein Diagnostics with Attomolar Sensitivity in Serum and Unprocessed Whole Blood," Analytical Chemistry, Vol. 85, No. 7, March/April 2013, pp. 3698-3706

8.) M. Cretich, M. R. Monroe, A. Reddington, X. Zhang, G. G. Daaboul, F. Damin, L. Sola, M. S. Ünlü, and M. Chiari, "Interferometric silicon biochips for label and label-free DNA and protein microarrays.," Proteomics, Vol. 12, 2013, pp. 2963-2977

7.) G. G. Daaboul, C. A. Lopez, A. Yurt, B. B. Goldberg, J. H. Connor, and M. S. Ünlü, "Optical Biosensors for Virus Detection and Characterization," IEEE Journal of Selected Topics in Quantum Electronics, Vol. 18, No. 4, July/August 2012, pp. 1422-1433

6.) A. Yurt, G. G. Daaboul, J. H. Connor, B. B. Goldberg, and M. S. Ünlü, "Single nanoparticle detectors for biological applications," Nanoscale, Vol. 4, No. 3, 2012, pp. 715 - 726

5.) C. A. Lopez, G. G. Daaboul, S. Ahn, A. Reddington, M. R. Monroe, X. Zhang, R. Irani, C. Yu, C. A. Genco, M. Cretich, M. Chiari, B. B. Goldberg, J. H. Connor, and M. S. Ünlü, "Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)," Journal of Visualized Experiments, Vol. 51, May 2011, pp. doi: 10.3791/2694.

4.) G. G. Daaboul, R. S. Vedula, S. Ahn, C. A. Lopez, A. Reddington, E. Ozkumur, and M. S. Ünlü, "LED-based Interferometric Reflectance Imaging Sensor for quantitative dynamic monitoring of biomolecular interactions," Biosensors and Bioelectronics, Vol. 26, January 2011, pp. 2221-2227

3.) C. A. Lopez, G. G. Daaboul, R. S. Vedula, E. Ozkumur, D. A. Bergstein, T. W. Geisbert, H. Fawcett, B. B. Goldberg, J. H. Connor, and M. S. Ünlü, "Label-free multiplexed virus detection using spectral reflectance imaging," Biosensors and Bioelectronics, 2011

2.) G. G. Daaboul, A. Yurt, X. Zhang, G. M. Hwang, B. B. Goldberg, and M. S. Ünlü, "High-Throughput Detection and Sizing of Individual Low-Index Nanoparticles and Viruses for Pathogen Identification," Nano Letters, Vol. 11, October 2010, pp. 4727-4731

1.) R. S. Vedula, G. G. Daaboul, A. Reddington, E. Ozkumur, D. A. Bergstein, and M. S. Ünlü, "Self-Referencing Substrates for Optical Interferometric Biosensors," Journal of Modern Optics, Vol. 57, No. 16, 20 September 2010, pp. 1564–1569

Conference Papers

8.) X. Zhang, G. G. Daaboul, P. S. Spuhler, D. S. Freedman, A. Yurt, S. Ahn, and M. S. Ünlü, "Quantification of DNA hybridization by nanoscale axial localization and label-free biosensing," BMES 2013 Annual Meeting , 22-25 October 2013

7.) G. G. Daaboul, P. F. Renda, R. R. Graef, A. Yurt, X. Zhang, C. A. Lopez, J. H. Connor, G. M. Hwang, B. B. Goldberg, and M. S. Ünlü, "IRIS:LED-interferometric reflectance imaging sensor for label-free detection of nanoparticles ," SPIE Photonics West 2011-BIOS, January 2011

6.) A. Yurt, G. G. Daaboul, X. Zhang, G. M. Hwang, B. B. Goldberg, and M. S. Ünlü, "Widefield Interferometric Detection and Size Determination of Dielectric Nanoparticles," Proceedings of IEEE Photonics Society 2010 Annual Meeting, 11 November 2010

5.) G. G. Daaboul, P. F. Renda, R. R. Graef, A. Yurt, X. Zhang, C. A. Lopez, J. H. Connor, B. B. Goldberg, G. M. Hwang, and M. S. Ünlü, "IRIS: Interferometric Reflectance Imaging Sensor for Virus Detection(Invited) ," Materials Research Society Proceeding Fall 2010, November 2010

4.) A. Yurt, G. G. Daaboul, X. Zhang, B. B. Goldberg, and M. S. Ünlü, "Spectral Scattering Imaging for Single Particle Detection and Size Discrimination," Nano-TR, June 2010

3.) G. G. Daaboul, C. A. Lopez, J. H. Connor, G. M. Hwang, O. Rabin, P. F. Renda, R. R. Graef, and M. S. Ünlü, "LED-based spectral reflectance imaging biosensor for label-free single pathogen detection," Biosensors, 2010, Glasgow, Scotland , May 2010

2.) G. G. Daaboul, R. S. Vedula, A. Reddington, E. Ozkumur, C. A. Lopez, J. H. Connor, H. Fawcett, and M. S. Ünlü, "LED-based spectral reflectance imaging biosensor for label-free high-throughput multi-analyte and single-pathogen detection ," SPIE Photonics West 2010 - BIOS, January/February 2010

1.) M. S. Ünlü, E. Ozkumur, C. A. Lopez, A. Yalcin, M. Chiari, S. Ahn, G. G. Daaboul, A. Reddington, M. R. Monroe, R. S. Vedula, and J. H. Connor, "Spectral reflectance imaging for a multiplexed, high-throughput, label-free, and dynamic biosensing platform: protein, DNA and virus detection," SPIE Photonics West 2010 - BIOS, No. Paper 7553-17 , 23-28 January 2010

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