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Optical Characterization and Nanophotonics Laboratory

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[Books & Chapters][Journal Articles][Conference Papers][Theses]

Xirui Zhang

Graduate Student
Doctor of Philosophy
Lab: 3-5887

Projects

Interferometric Reflectance Imaging Sensor

Biological Sensors

Self-Interference Fluorescence Microscopy

Books & Chapters

2.) X. Zhang, P. S. Spuhler, D. S. Freedman, and M. S. Ünlü, "Spectral Self-Interference Fluorescence Microscopy to Study Conformation of Biomolecules with Nanometer Accuracy," Nanoscale Spectroscopy with Applications, November 2013

1.) S. Ahn, D. S. Freedman, X. Zhang, and M. S. Ünlü, "High-throughput label-free detection of DNA hybridization and mismatch discrimination using interferometric reflectance imaging sensor," Nucleic Acid Detection: Methods in Molecular Biology, Vol. 1039, September 2013

Journal Articles

8.) X. Zhang, G. G. Daaboul, P. S. Spuhler, P. Dröge, and M. S. Ünlü, "Quantitative characterization of conformational-specific protein–DNA binding using a dual-spectral interferometric imaging biosensor," Nanoscale, No. DOI: 10.1039/C5NR067, 2016

7.) E. Cevik, G. G. Daaboul, X. Zhang, S. M. Scherr, N. Lortlar Ünlü, J. H. Connor, and M. S. Ünlü, "DNA-Directed Antibody Immobilization for Enhanced Detection of Single Viral Pathogens," Analytical Chemistry, Vol. 87, No. 20, October 2015, pp. 10505-10512, DOI:10.1021/acs.analchem.5b02702

6.) X. Zhang, G. G. Daaboul, P. S. Spuhler, D. S. Freedman, A. Yurt, S. Ahn, O. Avci, and M. S. Ünlü, "Nanoscale Characterization of DNA Conformation Using Dual-color Fluorescence Axial Localization and Label-free Biosensing," Analyst, 13 October 2014

5.) M. Cretich, M. R. Monroe, A. Reddington, X. Zhang, G. G. Daaboul, F. Damin, L. Sola, M. S. Ünlü, and M. Chiari, "Interferometric silicon biochips for label and label-free DNA and protein microarrays.," Proteomics, Vol. 12, 2013, pp. 2963-2977

4.) P. S. Spuhler, L. Sola, X. Zhang, M. R. Monroe, J. T. Greenspun, M. Chiari, and M. S. Ünlü, "Precisely Controlled Smart Polymer Scaffold for Nanoscale Manipulation of Biomolecules," Analytical Chemistry, Vol. 84, November 2012, pp. 10593–10599

3.) S. Ahn, C. Huang, E. Ozkumur, X. Zhang, J. Chinnala, A. Yalcin, S. Bandyopadhyay, S. Russek, M. S. Ünlü, C. DeLisi, and R. Irani, "TATA binding proteins can recognize nontraditional DNA sequences," Biophysical Journal, Vol. 103, October 2012, pp. 1510-1517

2.) C. A. Lopez, G. G. Daaboul, S. Ahn, A. Reddington, M. R. Monroe, X. Zhang, R. Irani, C. Yu, C. A. Genco, M. Cretich, M. Chiari, B. B. Goldberg, J. H. Connor, and M. S. Ünlü, "Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)," Journal of Visualized Experiments, Vol. 51, May 2011, pp. doi: 10.3791/2694.

1.) G. G. Daaboul, A. Yurt, X. Zhang, G. M. Hwang, B. B. Goldberg, and M. S. Ünlü, "High-Throughput Detection and Sizing of Individual Low-Index Nanoparticles and Viruses for Pathogen Identification," Nano Letters, Vol. 11, October 2010, pp. 4727-4731

Conference Papers

9.) X. Zhang, G. G. Daaboul, P. S. Spuhler, D. S. Freedman, A. Yurt, S. Ahn, and M. S. Ünlü, "Quantification of DNA hybridization by nanoscale axial localization and label-free biosensing," BMES 2013 Annual Meeting , 22-25 October 2013

8.) X. Zhang, P. S. Spuhler, L. Sola, M. Chiari, and M. S. Ünlü, "A high speed micro-arrayed biosensing platform for the detection of specific DNA-protein interactions," Biosensors, 2012, Cancun, Mexico, 15-18 May 2012

7.) P. S. Spuhler, L. Sola, X. Zhang, M. R. Monroe, J. T. Greenspun, M. Chiari, and M. S. Ünlü, "A Nano-Electromechanical Biosensor Based on Precise Quantification and Control of DNA Orientation," 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 3 September 2011

6.) P. S. Spuhler, L. Sola, X. Zhang, M. R. Monroe, J. T. Greenspun, M. Chiari, and M. S. Ünlü, "Precise Control of DNA Orientation for Improved Functionality in Protein Binding Microarrays," International Conference on Optical MEMS & Nanophotonics, August 2011

5.) G. G. Daaboul, P. F. Renda, R. R. Graef, A. Yurt, X. Zhang, C. A. Lopez, J. H. Connor, G. M. Hwang, B. B. Goldberg, and M. S. Ünlü, "IRIS:LED-interferometric reflectance imaging sensor for label-free detection of nanoparticles ," SPIE Photonics West 2011-BIOS, January 2011

4.) M. S. Ünlü, P. S. Spuhler, L. Sola, M. R. Monroe, X. Zhang, and M. Chiari, "A platform for the precise quantification of DNA orientation and conformation," USNC-URSI National Radio Science Meeting, January 2011

3.) A. Yurt, G. G. Daaboul, X. Zhang, G. M. Hwang, B. B. Goldberg, and M. S. Ünlü, "Widefield Interferometric Detection and Size Determination of Dielectric Nanoparticles," Proceedings of IEEE Photonics Society 2010 Annual Meeting, 11 November 2010

2.) G. G. Daaboul, P. F. Renda, R. R. Graef, A. Yurt, X. Zhang, C. A. Lopez, J. H. Connor, B. B. Goldberg, G. M. Hwang, and M. S. Ünlü, "IRIS: Interferometric Reflectance Imaging Sensor for Virus Detection(Invited) ," Materials Research Society Proceeding Fall 2010, November 2010

1.) A. Yurt, G. G. Daaboul, X. Zhang, B. B. Goldberg, and M. S. Ünlü, "Spectral Scattering Imaging for Single Particle Detection and Size Discrimination," Nano-TR, June 2010

Theses

1.) X. Zhang, "Dual-spectral Interferometric Sensor for Quantitative Study of Protein-DNA Interactions," Ph.D. Dissertation, August 2014

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